Building a Complete Polar Metabolomics Solution with Capillary Electrophoresis-Mass Spectrometry (CE-MS)

Analytical labs using CE-MS for polar metabolite analysis need more than high-resolution separations—they need a complete, reproducible metabolomics workflow that delivers accurate quantitative results while meeting system suitability and quality control requirements. Many labs face ongoing challenges such as sample preparation, calibration, QC monitoring, and data processing. These steps are essential for reliable CE-MS metabolomics, yet they often require significant manual effort, custom methods, and ongoing troubleshooting, slowing productivity and increasing variability across runs and users.

MoveKit CE paired with the PATsmart™ ZipChip® microfluidic CE-MS platform offers exceptional separation performance and is designed to address these common lab challenges by ensuring ZipChip CE-MS is a fully integrated solution for polar metabolite analysis. This solution provides the standards, calibration materials, QC components, and consumables needed for consistent sample preparation, along with MoveApp software to support experimental design, automatically monitor system suitability, perform real-time QC checks, and rapidly process CE-MS data in minutes.

In this webinar, you’ll learn how MoveKit CE helps laboratories streamline CE-MS workflows for polar metabolomics, reduce manual work, improve data confidence, and unlock the full value of their ZipChip CE-MS system—from raw samples to validated quantitative results.

Learning Objectives:

  • Learn how high-resolution CE-MS separations optimize metabolomics and growth media characterization workflows
  • Develop easy-to-adopt strategies to address potential roadblocks for polar metabolomics
  • How MoveKit CE enhances the ZipChip CE-MS platform to deliver a complete end-to-end workflow for metabolomics

Speakers

 

Hampus Engstroem 

Hampus Engstroem

Repligen
Field Application & Marketing Manager

Hampus Engstroem is a Field Applications & Marketing Manager at Repligen, where he supports and drives adoption of the ZipChip® CE-MS and REBEL® XT Media Analyzer platforms. He brings over a decade of hands-on experience in mass spectrometry and molecular biology, with a strong focus on translating complex analytical technologies into practical, high-impact workflows for biopharma and research applications.

Prior to joining Repligen, Hampus held multiple roles at 908 Devices, including Field Application Scientist, Team Lead for the North American Field Applications organization, and Product Management Liaison for the ZipChip CE-MS product, where he played a key role in customer support, product development feedback, and market positioning. Earlier in his career, he managed the George L. Wright Jr. Center for Biomedical Proteomics core at the Leroy T. Canoles Jr. Cancer Research Center at Eastern Virginia Medical School, overseeing advanced proteomics workflows and supporting translational cancer research.

Scott Mellors, Ph.D.

Scott Mellors, Ph.D.

Move Analytical
Founding Partner and Science Lead

Dr. J. Scott Mellors is Founding Partner and Science Lead at Move Analytical, where he leads production efforts as well as the translation of research ideas into practical customer tools. With over two decades of experience in analytical chemistry and instrumentation, Dr. Mellors is widely recognized as an expert in capillary electrophoresis-mass spectrometry (CE-MS) and ultrahigh-pressure liquid chromatography (UHPLC).

Scott earned his Ph.D. in Chemistry from the University of North Carolina at Chapel Hill in 2005, conducting research on UHPLC under the mentorship of Professor James Jorgenson. He subsequently joined the laboratory of Professor J. Michael Ramsey as a staff scientist, focusing on integrating microfluidic separations with mass spectrometry. During his tenure, he led the microchip electrospray ionization (ESI) subgroup, contributing to advancements in microfluidic CE-MS systems.

In 2014, Scott joined 908 Devices as a Principal Scientist, where he played a pivotal role in the development of the ZipChip® and REBEL platforms. These innovations have enhanced analytical workflows by providing rapid, high-resolution separations with minimal sample preparation. His work has been instrumental in advancing CE-MS technology for antibody characterization and metabolomics applications.


Published

February 12, 2026

Created by

The Analytical Scientist Webinars